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Nicholas G Smedira Selected Research

Left Ventricular Outflow Obstruction

1/2022Comprehensive left ventricular outflow tract management beyond septal reduction to relieve obstruction.
1/2022Impact of left atrial strain mechanics on exercise intolerance and need for septal reduction therapy in hypertrophic cardiomyopathy.
10/2015Symptom assessment and exercise impairment in surgical decision making in hypertrophic obstructive cardiomyopathy: Relationship to outcomes.
5/2015Predictors of long-term outcomes in patients with hypertrophic cardiomyopathy undergoing cardiopulmonary stress testing and echocardiography.
1/2014Exercise echocardiography in asymptomatic HCM: exercise capacity, and not LV outflow tract gradient predicts long-term outcomes.
7/2013Predictors of long-term outcomes in symptomatic hypertrophic obstructive cardiomyopathy patients undergoing surgical relief of left ventricular outflow tract obstruction.
12/2004Use of the Alfieri edge-to-edge technique to eliminate left ventricular outflow tract obstruction caused by mitral systolic anterior motion.

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Nicholas G Smedira Research Topics

Disease

19Heart Failure
01/2018 - 11/2002
16Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
12/2022 - 04/2003
7Left Ventricular Outflow Obstruction
01/2022 - 12/2004
7Atrial Fibrillation
10/2017 - 10/2002
6Stroke (Strokes)
05/2015 - 09/2002
5Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2021 - 11/2010
5Thrombosis (Thrombus)
10/2019 - 02/2007
5Hemorrhage
01/2019 - 03/2006
4Cardiomyopathies (Cardiomyopathy)
01/2021 - 02/2006
3Cardiogenic Shock
08/2017 - 02/2003
3Heart Diseases (Heart Disease)
05/2017 - 11/2011
3Infections
10/2015 - 07/2006
3Coronary Artery Disease (Coronary Atherosclerosis)
03/2007 - 01/2006
2Hemolysis
10/2019 - 01/2014
2Myocardial Infarction
08/2017 - 08/2014
2Neoplasms (Cancer)
05/2017 - 10/2003
2Cardiac Arrhythmias (Arrythmia)
07/2015 - 02/2013
2Sudden Death
05/2015 - 07/2013
2Mitral Valve Insufficiency (Mitral Regurgitation)
01/2014 - 12/2004
2Left Ventricular Dysfunction
02/2013 - 02/2007
2Ventricular Tachycardia
06/2012 - 04/2010
2Bradycardia
11/2010 - 08/2009
2Diabetes Mellitus
07/2006 - 01/2006
2Arteriosclerosis
07/2006 - 01/2006
1Clinical Deterioration
01/2022
1Syncope (Fainting)
01/2021
1Wounds and Injuries (Trauma)
01/2019
1Hypertension (High Blood Pressure)
11/2017
1Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2017
1Death (Near-Death Experience)
10/2017
1Ascending Aorta Dissection
08/2017
1Aortic Dissection
08/2017
1Anterior Wall Myocardial Infarction
08/2017
1Aortic Valve Stenosis (Aortic Stenosis)
05/2017
1Aortic Valve Insufficiency (Aortic Regurgitation)
03/2016
1Acute Kidney Injury (Acute Renal Failure)
12/2015
1Bacteremia
10/2015
1Ventricular Septal Rupture
08/2014
1Fibrosis (Cirrhosis)
08/2014
1Pulmonary Fibrosis (Fibrosing Alveolitis)
08/2014
1Bronchiectasis
08/2014
1Aneurysm (Aneurysms)
06/2013
1Ventricular Dysfunction
02/2013
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2012
1Heroin Dependence (Heroin Abuse)
04/2010
1Marijuana Use
04/2010
1Narcotic-Related Disorders
04/2010
1Postoperative Pain
10/2007
1Substance-Related Disorders (Drug Abuse)
03/2007

Drug/Important Bio-Agent (IBA)

2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2019 - 01/2014
2Pharmaceutical PreparationsIBA
04/2010 - 03/2007
2Heparin (Liquaemin)FDA LinkGeneric
02/2007 - 03/2006
2bivalirudin (Angiomax)FDA Link
02/2007 - 03/2006
2HDL LipoproteinsIBA
07/2006 - 01/2006
2Triglycerides (Triacylglycerol)IBA
07/2006 - 01/2006
1Myosins (Myosin)IBA
12/2022
1MYK-461IBA
01/2021
1pro-brain natriuretic peptide (1-76)IBA
01/2021
1TroponinIBA
01/2021
1Lactate Dehydrogenase 5IBA
10/2019
1Biomarkers (Surrogate Marker)IBA
10/2019
1GadoliniumIBA
01/2018
1AlbuminsIBA
11/2017
1Biological ProductsIBA
03/2016
1Dihydrotachysterol (AT 10)IBA
03/2016
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
05/2015
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
08/2014
1Polytetrafluoroethylene (Teflon)FDA Link
06/2013
1Amyloid (Amyloid Fibrils)IBA
12/2012
1Cocaine (Cocaine HCl)IBA
04/2010
1Dichlorodiphenyldichloroethane (DDD)IBA
08/2009
1Tuberculin (PPD)IBA
03/2007

Therapy/Procedure

18Therapeutics
12/2022 - 02/2006
15Transplantation
01/2018 - 10/2003
14Heart-Assist Devices
10/2019 - 08/2002
8Coronary Artery Bypass (Coronary Artery Bypass Surgery)
11/2017 - 08/2003
8Heart Transplantation (Grafting, Heart)
01/2014 - 02/2003
6Defibrillators (Defibrillator)
01/2021 - 02/2013
4Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2018 - 02/2013
3Artificial Heart (Artificial Hearts)
08/2017 - 03/2003
3Sternotomy
07/2014 - 09/2007
3Cardiopulmonary Bypass (Heart-Lung Bypass)
02/2007 - 12/2004
3Maze Procedure
08/2006 - 10/2002
2Operative Surgical Procedures
01/2022 - 08/2010
2Blood Transfusion (Blood Transfusions)
12/2015 - 08/2003
2Conservative Treatment
10/2015 - 10/2015
2Catheter Ablation
07/2015 - 06/2012
2Myotomy
06/2014 - 04/2003
2Operative Time
10/2007 - 03/2006
1Negative-Pressure Wound Therapy
01/2019
1Replantation
11/2017
1Radiotherapy
05/2017
1Anticoagulation Reversal
08/2015
1Catheters
07/2015
1Percutaneous Coronary Intervention
08/2014
1Traction
08/2014
1Complementary Therapies (Alternative Medicine)
06/2013
1Liver Transplantation
11/2011
1Tattooing
04/2010
1Thoracotomy
09/2007